Drug Standards
Medchemexpress LLC Fenticonazole Nitrate | 73151-29-8 | 98.9% | 1 ML
Fenticonazole Nitrate is an antifungal imidazole ring derivative. It functions by hindering ergosterol integration, which in turn destructs the cytoplasmatic outer membrane. Fenticonazole Nitrate is effective against Gram-positive bacteria, mycoses, and vaginal candidiasis.
- Antifungal imidazole ring derivative
- Hinders ergosterol integration
- Destroys the cytoplasmatic outer membrane
- Effective against Gram-positive bacteria
- Effective against mycoses
- Effective against vaginal candidiasis
Apexbio Technology LLC (+)-Ketoconazole 142128-59-4 10mg
( )-Ketoconazole (CAS 142128-59-4) is a small-molecule inhibitor targeting cytochrome P450 enzymes primarily CYP3A4 and P450c17 (CYP17A1) It is designed to inhibit these enzymes thereby blocking steroidogenesis pathways and reducing androgen biosynthesis ( )-Ketoconazole exerts its biological activity primarily through inhibition of CYP3A4 and CYP17A1 In in vitro studies ( )-Ketoconazole demonstrates inhibitory activity with reported IC50 values in the low nanomolar to submicromolar range Based on these pharmacological properties ( )-Ketoconazole holds research potential in studying steroid hormone biosynthesis pathways and the biological functions regulated by cytochrome P450 enzyme activity particularly in investigations involving androgen-dependent cell models and related endocrine mechanisms
Medchemexpress LLC Rosuvastatin Calcium | 147098-20-2 | 99.8% | 520.61 | 50 MG
Rosuvastatin Calcium is a competitive HMG-CoA reductase (HMGCR) inhibitor, with an IC50 of 11 nM. Rosuvastatin Calcium potently blocks hERG current with an IC50 of 195 nM. It reduces the expression of the mature hERG and the interaction of heat shock protein 70 (Hsp70) with the hERG protein. Rosuvastatin Calcium effectively lowers low-density lipoprotein (LDL) cholesterol, triglycerides, and C-reactive protein levels.
- Competitive HMG-CoA reductase (HMGCR) inhibitor with an IC50 of 11 nM
- Potently blocks hERG current with an IC50 of 195 nM
- Reduces the expression of the mature hERG and the interaction of heat shock protein 70 (Hsp70) with the hERG protein
- Effectively lowers low-density lipoprotein (LDL) cholesterol, triglycerides, and C-reactive protein levels
Selleck Chemical LLC Felodipine S1885-10mg
Felodipine (CGH-869) is a selective L-type Ca2 channel blocker with IC50 of 0 15 nM
Sigma Aldrich Fine Chemicals Biosciences Dantrolene Related Compound B United States Pharmacopeia (USP) Reference Standard | 57268-33-4 | 50MG
Dantrolene Related Compound B United States Pharmacopeia (USP) Reference Standard | Mol Wt: 332.27 | 57268-33-4 | 50MG
Medchemexpress LLC Oxfendazole | 53716-50-0 | 98.8% | 500 MG
Oxfendazole is a sulfoxide form of fenbendazole that is effective when taken orally. It fights parasites and has tumor-promoting activity. This product is for research use only.
- Sulfoxide form of fenbendazole
- Effective when taken orally
- Fights parasites
- Promotes tumor activity
- For research use only
- Effective against gastrointestinal nematodes in pigs
Medchemexpress LLC Eupatilin | 22368-21-4 | 344.32 | 25 MG
Eupatilin is a lipophilic flavonoid isolated from Artemisia argyi Lévl. et Van. It acts as a PPARα agonist and exhibits anti-apoptotic, anti-oxidative, and anti-inflammatory activities. It is for research use only and not for sale to patients. This compound appears as a light yellow to yellow solid with the formula C18H16O7 and is classified as a flavonoid.
- Acts as a PPARα agonist.
- Exhibits anti-apoptotic, anti-oxidative, and anti-inflammatory activities.
- Isolated from Artemisia argyi Lévl. et Van.
- Appears as a light yellow to yellow solid.
- Has the chemical formula C18H16O7.
- Classified as a flavonoid.
- Intended for research use only.
Selleck Chemical LLC Carbidopa S1891-100mg
Carbidopa is an aromatic-L-amino-acid decarboxylase inhibitor with an IC50 of 29 2 M
Medchemexpress LLC Tofacitinib | 477600-75-2 | 99.9% | 312.37 | 1 G
Tofacitinib is an orally available JAK3/2/1 inhibitor, with IC50s of 1, 20, and 112 nM, respectively. It is intended for research use only as a laboratory chemical and for the manufacture of substances. This product has not been fully validated for medical applications.
- Identified for research use
- Stable under recommended storage conditions
- Keep container tightly sealed in cool, well-ventilated area
- Store powder at -20°C for 3 years or 4°C for 2 years
- Store in solvent at -80°C for 2 years or -20°C for 1 year
- Ships at room temperature if less than 2 weeks
Selleck Chemical LLC Tenofovir S1401-10mM/1mL
Tenofovir (GS-1278) blocks reverse transcriptase and hepatitis B virus infections
Med Vet International Ohio Female to Barbed Suction Connector, J0535FS, Each
Ohio Female to Barbed Suction Connector, J0535FS, Each
Apexbio Technology LLC R788 disodium 1025687-58-4 100mg
R788 disodium (CAS 1025687-58-4) is a prodrug of the active metabolite R406 a selective inhibitor of spleen tyrosine kinase (Syk) Syk mediates signaling downstream of activated Fc and B-cell receptors (BCR) In vitro R406 suppresses constitutive and ligand-stimulated BCR signaling in diffuse large B-cell lymphoma (DLBCL) lines by inhibiting Syk autophosphorylation (SYK525/526) and associated phosphorylation of BLNK inducing apoptosis In vivo R788 reduces malignant B-cell proliferation and tumor progression in E -TCL1 mice Clinically R788 has shown utility in rheumatoid arthritis improving therapeutic response rates in phase II trials
Selleck Chemical LLC Zonisamide 25mg 68291-97-4 CI-912
Zonisamide (CI-912) is a voltage-dependent sodium channel and T-type calcium channel blocker, used as an antiepileptic drug. *For Research & Development use only. Product is not intended for drug, household, or human consumption.
Sigma Aldrich Fine Chemicals Biosciences Idoxuridine European Pharmacopoeia (EP) Reference Standard | 54-42-2 | MFCD00134656 |
Idoxuridine European Pharmacopoeia (EP) Reference Standard | Mol Wt: 354.1 | 54-42-2 | MFCD00134656 |
Sigma Aldrich Fine Chemicals Biosciences Mitomycin European Pharmacopoeia (EP) Reference Standard | 50-07-7 |
Mitomycin European Pharmacopoeia (EP) Reference Standard | Mol Wt: 334.33 | 50-07-7 |